生长抑素受体4抗体
规格：1mg/1ml
英文名： SSTR4
别名： somatostatin receptor 4; Smstr4; Somatostatin receptor type 4; SS 4R; SS4R; SST R4; SSTR 4; SSTR4; SSR4_HUMAN.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SSTR4
交叉反应：Human, Mouse, Rat, Pig, Rabbit,
细胞定位：细胞膜
生长抑素受体4抗体产品介绍：background: Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and ***** brain and lung. Its function is to inhibit the release of many hormones and other secretory proteins. Function: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative生长抑素受体4抗体 action of somatostatin in tumor cells. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Specifically expressed in fetal and ***** brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.生长抑素受体4抗体 Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 6754 Database links: Entrez Gene: 6754 Human Entrez Gene: 20608 Mouse Entrez Gene: 25555 Rat Omim: 182454 Human SwissProt: P31391 Human SwissProt: P49660 Mouse SwissProt: P30937 Rat Unigene: 673846 Human Unigene: 35324 Mouse Unigene: 9936 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长抑素受体4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid