NALP5蛋白抗体
规格:1mg/1ml
英文名: NALP5
别名: CLR19.8; MATER; Mater protein homolog; Maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; NALP5_HUMAN; NLR family,
分子量: 134kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NALP5
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核 细胞浆
NALP5蛋白抗体产品介绍:background: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008] Function: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions Subunit: Component of the SCMC which also includes at least OOEP and TLE6 Subcellular Location: Mitochondrion. Nucleus > nucleolus. Cytoplasm. In the subcortical cNALP5蛋白抗体ytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions. Tissue Specificity: Oocyte-specific. Similarity: Belongs to the NLRP family. Contains 1 DAPIN domain.NALP5蛋白抗体 Contains 13 LRR (leucine-rich) repeats. Contains 1 NACHT domain. Database links: Entrez Gene: 126206 Human Entrez Gene: 23968 Mouse Entrez Gene: 308325 Rat Omim: 609658 Human SwissProt: P59047 Human SwissProt: Q9R1M5 Mouse Unigene: 356872 Human Unigene: 333653 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NALP5蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 信号转导 干细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid