Naked1蛋白抗体
规格:1mg/1ml
英文名: Naked1
别名: Dvl-binding protein; Naked cuticle 1; naked cuticle 1 homolog; Naked cuticle homolog 1 (Drosophila); Naked-1; NKD; Nkd1; Protein naked cuticle homolog 1.
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Naked1
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞膜
Naked1蛋白抗体产品介绍:background: In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003] Function: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Subunit: Interacts with DVL1, DVL2, DVL3 and PPP2R3A. Subcellular Location: CelNaked1蛋白抗体l membrane By similarity. Cytoplasm Tissue Specificity: Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen. Similarity: Belongs to the NKD family. Contains 1 EF-hand domain. Gene ID: 85407 Database links: Entrez Gene: 85407 Human Entrez Gene: 93960 Mouse Entrez Gene: 364952 Rat Omim: 607851 Human SwissProt: Q969G9 Naked1蛋白抗体Human SwissProt: Q99MH6 Mouse Unigene: 187578 Human Unigene: 30219 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Naked1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 干细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid