NACA2蛋白抗体
规格：1mg/1ml
英文名： NACA2
别名： Alpha NAC like; ANAC; Hom s 2.01; MGC71999; NAC alpha like; NACA2; NACAL; nascent polypeptide associated complex alpha polypeptide like; Nascent polypeptide associated complex subunit alpha 2.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NACA2
交叉反应：Human,
细胞定位：细胞核 细胞浆
NACA2蛋白抗体产品介绍：background: NACA2, Nascent polypeptide associated complex subunit alpha 2, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) by binding to nascent polypeptide chains as they emerge from the ribosome and blocking their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. NACA2 also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). Function: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity NACA2蛋白抗体of ribosomes for protein translocation sites in the ER membrane (M sites) Subunit: Part of the nascent polypeptide-associated complex (NAC), consisting of NACA and BTF3. NAC associates with ribosomes through the BTF3 subunit. Both subunits can contact nascent polypeptide chains Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Expressed specifically in testis and skeletal muscle. Similarity: NACA2蛋白抗体Belongs to the NAC-alpha family. Contains 1 NAC-A/B (NAC-alpha/beta) domain. Contains 1 UBA domain. Gene ID: 342538 Database links: Entrez Gene: 342538 Human GenBank: NM_199290.3 Human Omim: 609274 Human SwissProt: Q9H009 Human Important Note: This product as supplied is intended for research use only, not for use in human, NACA2蛋白抗体therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid