NAALADL2蛋白抗体
规格：1mg/1ml
英文名： NAALADL2
别名： Glutamate carboxypeptidase II type non peptidase homologue; Inactive N acetylated alpha linked acidic dipeptidase like protein 2; Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2;
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NAALADL2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, Saccharomyces cerevisiae
NAALADL2蛋白抗体细胞定位：细胞膜
产品介绍：background: NAALADL2 is a 795 amino acid single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. Existing as two alternatively spliced isoforms, NAALADL2 is expressed at highest levels in placenta and kidney, and has also been observed in certain embryonic tissues. NAALADL2 may be catalytically inactive. The gene encoding NAALADL2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator NAALADL2蛋白抗体HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: May be catalytically inactive. Subcellular Location: Membrane. Tissue Specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to NAALADL2蛋白抗体duodenal and stomach endoderm, mesonephros, metanephros and pancreas. Similarity: Belongs to the peptidase M28 family. M28B subfamily. Database links: Entrez Gene: 254827 Human Entrez Gene: 635702 Mouse Entrez Gene: 499583 Rat Omim: 608806 Human SwissProt: Q58DX5 Human Unigene: 565848 Human Unigene: 603646 Human Unigene: 660010 Human Unigene: 448351 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NAALADL2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid