E3泛素连接酶NEDD4结合蛋白2抗体
规格：1mg/1ml
英文名： N4BP2
别名： B3BP; BCL 3 binding protein; BCL3 binding protein; FLJ10680; KIAA1413; Nedd4 binding protein 2.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human N4BP2
交叉反应：Human,
细胞定位：细胞浆
E3泛素连接酶NEDD4结合蛋白2抗体产品介绍：background: This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq, Jul 2008] Function: Has 5'-polynucleotide kinase and nicking E3泛素连接酶NEDD4结合蛋白2抗体endonuclease activity. May play a role in DNA repair or recombination. Subunit: E3泛素连接酶NEDD4结合蛋白2抗体Binds NEDD4 By similarity. Binds BCL3 and CREBBP. Subcellular Location: Cytoplasm Post-translational modifications: Ubiquitinated; this targets the protein for degradation by the proteasome Similarity: Contains 1 CUE domain. Contains 1 Smr domain. Database links: Entrez Gene: 55728 Human SwissProt: Q86UW6 Human Unigene: 396494 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
E3泛素连接酶NEDD4结合蛋白2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid