丝裂原活化蛋白激酶激酶激酶4抗体
规格：1mg/1ml
英文名： MLK4
别名： dJ862P8.3; KIAA1804; M3KL4_HUMAN; Mitogen activated protein kinase kinase kinase; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4; MLK 4; Mlk4; RP5 862P8.2.
分子量： 114kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MLK4
交叉反应：Human, Mouse, Rat,
丝裂原活化蛋白激酶激酶激酶4抗体细胞定位：细胞浆
产品介绍：background: Mixed lineage kinases are a family of protein kinases sharing two leucine zipper-like motifs, which are known to mediate protein dimerization and a kinase domain whose primary structure is similar to both the tyrosine-specific and the serine/threonine-specific kinase classes. Members of the mixed-lineage kinase (MLK) family include MLK1, MLK2, MLK3, MLK4, MELK, LZK and dual leucine zipper kinase, also designated DLK. MLKs are expressed in neuronal cells where they are likely to interact between Rac1/Cdc42, MKK4 and丝裂原活化蛋白激酶激酶激酶4抗体 MKK7 in death signaling Function: Activates the JUN N-terminal pathway. Post-translational modifications: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Similarity: Belongs to the 丝裂原活化蛋白激酶激酶激酶4抗体protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain. Contains 1 SH3 domain. Database links: Entrez Gene: 84451 Human SwissProt: Q5TCX8 Human Unigene: 547779 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝裂原活化蛋白激酶激酶激酶4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit