丝裂原活化蛋白激酶激酶激酶10抗体
规格：1mg/1ml
英文名： MLK2/MAP3K10
别名： M3K10_HUMAN; MAP3K 10; MAP3K10; MEKK10; Mitogen activated protein kinase kinase kinase 10; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; MKN28 derived nonreceptor type ser
分子量： 103kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MLK2/MAP
交叉反应：Human, Mouse, Rat, Xenopus laevis
细胞定位：细胞浆
丝裂原活化蛋白激酶激酶激酶10抗体产品介绍：background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008] Function: Activates the JUN N-terminal pathway. Tissue Specificity: Expressed in brain and skeletal muscle. Post-translational modifications: Autophosphorylation on serine and threonine residues within the activation丝裂原活化蛋白激酶激酶激酶10抗体 loop plays a role in enzyme activation. Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain. Contains 1 SH3 domain. Database l丝裂原活化蛋白激酶激酶激酶10抗体inks: Entrez Gene: 4294 Human Entrez Gene: 269881 Mouse Entrez Gene: 308463 Rat Entrez Gene: 398612 Xenopus laevis Omim: 600137 Human SwissProt: Q02779 Human SwissProt: Q66L42 Mouse SwissProt: Q7T2V3 Xenopus laevis Unigene: 466743 Human Unigene: 389883 Mouse Unigene: 26500 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝裂原活化蛋白激酶激酶激酶10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞凋亡 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid