巨核细胞白血病2抗体
规格：1mg/1ml
英文名： MKL2
别名： FLJ31823; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; MKL/myocardin-like 2; MKL/myocardin-like protein 2; Mkl2; MKL2_HUMAN; MRTF-B; Myocardin-related transcription factor B; NPD0
分子量： 118kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MKKS
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
巨核细胞白血病2抗体产品介绍：background: This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene 巨核细胞白血病2抗体have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] Function: Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation. Subunit: Interacts with MKL1 and SRF. Subcellular Location: 巨核细胞白血病2抗体Nucleus. Tissue Specificity: Widely expressed in ***** and fetal tissues. Similarity: Belongs to the TCP-1 chaperonin family. Database links: Entrez Gene: 57496 Human Entrez Gene: 239719 Mouse Entrez Gene: 100362470 Rat Omim: 609463 Human SwissProt: Q9ULH7 Human SwissProt: P59759 Mouse Unigene: 49143 Human Unigene: 270643 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巨核细胞白血病2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid