多聚磷酸肌醇磷酸酶1抗体
规格：1mg/1ml
英文名： MINPP1
别名： 5)-tetrakisphosphate 3-phosphatase; 5)P(4) 3-phosphatase; DKFZp564L2016; HIPER1; Inositol (1; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1; ins(1,3,4,5)P(4) 3-phosphatase; MINP1_HUMAN; Mi
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MINPP1
交叉反应：Human, Mouse, Rat,
细胞定位：
多聚磷酸肌醇磷酸酶1抗体产品介绍：background: This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009] Function: Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate 多聚磷酸肌醇磷酸酶1抗体(InsP5) and inositol hexakisphosphate (InsP6) (By similarity). May play a role in bone development (endochondral ossification). Subcellular Location: Endoplasmic reticulum lumen. Tissue Specificity: Widely expressed with highest levels in kidney, liver and placenta. DISEASE: Note=Defects in MINPP1 may be involved in follicular thyroid tumors development. Database links: Entrez Gene: 9562 Human 多聚磷酸肌醇磷酸酶1抗体Entrez Gene: 17330 Mouse Entrez Gene: 29688 Rat Omim: 605391 Human SwissProt: Q9UNW1 Human SwissProt: Q9Z2L6 Mouse SwissProt: O35217 Rat Unigene: 121260 Human Unigene: 255116 Mouse Unigene: 398664 Mouse Unigene: 27882 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多聚磷酸肌醇磷酸酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid