中胚层诱导早期反应蛋白1抗体
规格：1mg/1ml
英文名： MIER1
别名： ER1; Mesoderm induction early response 1; Mesoderm induction early response 1 homolog (Xenopus laevis); MI-ER1
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MIER1
交叉反应：Mouse, Rat, Dog, Cow, Zebrafish,
细胞定位：细胞核 细胞浆
中胚层诱导早期反应蛋白1抗体产品介绍：background: This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013] Function: Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing. Subunit: Interacts with HDAC1. Part of a complex containing at least CDYL中胚层诱导早期反应蛋白1抗体, MIER1, MIER2, HDAC1 and HDAC2. Tissue Specificity: Ubiquitously expressed, but at very low levels. However, consistent level of expression are observed in heart, testis, thyroid, ovary and adrenal gland. Transcripts are up-regulated in breast carcinoma cell lines and tumor. Similarity: Contains 1 ELM2 domain. Contains 1 SANT domain. Database links: Entrez Gene: 57708 Human Entrez Gene: 71148 中胚层诱导早期反应蛋白1抗体Mouse SwissProt: Q6NXT7 Human SwissProt: Q8N108 Human SwissProt: Q8N156 Human SwissProt: Q8N161 Human SwissProt: Q8NES4 Human SwissProt: Q8NES5 Human SwissProt: Q8NES6 Human SwissProt: Q5UAK0 Mouse SwissProt: Q5UAK1 Mouse SwissProt: Q5UAK2 Mouse SwissProt: Q5UAK3 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中胚层诱导早期反应蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid