MICAL样蛋白1抗体
规格：1mg/1ml
英文名： MICALL1/MIRab13
别名： DKFZp686M2226; FLJ45921; KIAA1668; MICAL-L1; MICAL-like 1; MICAL-like protein 1; Micall1; MILK1_HUMAN; MIRab13; Molecule interacting with Rab13.
分子量： 93kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MICALL1/
交叉反应：Human,
细胞定位：细胞浆
MICAL样蛋白1抗体产品介绍：background: MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22MICAL样蛋白1抗体 which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Function: May be a cytoskeletal regulator. Subcellular Location: Cytoplasm > cytoskeleton. Similarity: Contains 1 CH (calponin-homology) domain. MICAL样蛋白1抗体Contains 1 LIM zinc-binding domain. Database links: Entrez Gene: 85377 Human SwissProt: Q8N3F8 Human Unigene: 517610 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MICAL样蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid