MGAT5B蛋白抗体
规格：1mg/1ml
英文名： MGAT5B
别名： 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; 6-N-acetylglucosaminyltransferase B; Alpha-1; Alpha-mannoside beta-1; GlcNAc-T Vb; GNT-IX; GNT-Vb; hGnTVb; Mannoside acetylglucosaminyl
分子量： 90kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MGAT5B
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：
MGAT5B蛋白抗体产品介绍：background: The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008] Function: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl MGAT5B蛋白抗体glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Predominantly expressed in brain. Expressed in all area of the ***** and fetal brain Also expressed at much lower level in testis, spleen and thymus. Similarity: BelongsMGAT5B蛋白抗体 to the glycosyltransferase 18 family. Gene ID: 146664 Database links: Entrez Gene: 146664 Human Entrez Gene: 268510 Mouse Entrez Gene: 303693 Rat NCBI: NP_001100538.1 Rat Omim: 612441 Human SwissProt: Q3V5L5 Human SwissProt: Q765H6 Mouse Unigene: 144531 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MGAT5B蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid