MGAT4C蛋白抗体
规格:1mg/1ml
英文名: MGAT4C
别名: 3-D-mannoside beta-1; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; 4-N-acetylglucosaminyltransferase IVc; Alpha-1; GlcNAc-T IVc; GnT-IVc; hGnT-IV-H; MGAT4C; MGT4C_HUMAN; N-acetylg
分子量: 56kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MGAT4C
交叉反应:Human, Mouse, Rat,
细胞定位:
MGAT4C蛋白抗体产品介绍:background: MGAT4C is a 478 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the glycosyltransferase 54 family. Expressed in liver, heart, testis, brain and adrenal gland, GnT-IVH functions as a glycosyltransferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans, thereby playing a crucial role in the production of tri- and tetra-antennary N-linked sugar chains. The gene encoding GnT-IVH maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Function: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 MGAT4C蛋白抗体branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in heart, adrenal gland,MGAT4C蛋白抗体 testis, liver, brain and fetal brain. Not expressed in pancreas. Similarity: Belongs to the glycosyltransferase 54 family. Database links: Entrez Gene: 25834 Human SwissProt: Q9UBM8 Human Unigene: 589093 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MGAT4C蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid