MFSD6蛋白抗体
规格：1mg/1ml
英文名： MFSD6
别名： FLJ20160; HMMR2; macrophage MHC class I receptor 2 homolog; Macrophage MHC class I receptor 2 homolog; Macrophage MHC receptor 2; Major facilitator superfamily domain containing protein 6; MFSD6; MMR2
分子量： 88kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MFSD6
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
MFSD6蛋白抗体产品介绍：background: MFSD6L is a 586 amino acid multi-pass membrane protein of the MFSD6 family and major facilitator superfamily. The gene encoding MFSD6L maps to human chromosome 17, which contains about 81 million bases and 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though it is specifically recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. ChromosomeMFSD6蛋白抗体 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Subunit: May interact with HLA-B62. Subcellular Location: Membrane Tissue Specificity: Widely expressed. MFSD6蛋白抗体Expression levels in peripheral blood mononuclear cells are highly variable between individuals, including no expression at all. Similarity: Belongs to the major facilitator superfamily. MFSD6 family. Database links: Entrez Gene: 54842 Human Omim: 613476 Human SwissProt: Q6ZSS7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MFSD6蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid