黑色素瘤相关抗原P97抗体
规格：1mg/1ml
英文名： MFI2/MAP97
别名： Antigen p97; CD228; CD228 antigen; MAP97; Melanoma associated antigen p97; Melanoma-associated antigen p97; Melanotransferrin; Mfi2; MTF1; TRFM_HUMAN.
分子量： 37, 70, 85kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MFI2/MAP
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
黑色素瘤相关抗原P97抗体产品介绍：background: The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008] Function: Involved in iron cellular uptake. 黑色素瘤相关抗原P97抗体Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. Subcellular Location: Cell membrane. Tissue Specificity: Found predominantly in human melanomas and in certain 黑色素瘤相关抗原P97抗体fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts. Similarity: Belongs to the transferrin family. Contains 2 transferrin-like domains. Database links: Entrez Gene: 4241 Human Omim: 155750 Human SwissProt: P08582 Human Unigene: 184727 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑色素瘤相关抗原P97抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid