Rab4相互作用蛋白抗体
规格：1mg/1ml
英文名： RUFY1
别名： 3000002E04Rik; FLJ22251; FYVE finger protein EIP1; FYVE-finger protein EIP1; La binding protein 1; La-binding protein 1; OTTHUMP00000161521; Rab4 interacting protein; Rab4-interacting protein; RABIP4;
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RUFY1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
Rab4相互作用蛋白抗体产品介绍：background: This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. Subcellular Location: Cytoplasm. Early endosome membrane. Tissue Specificity:Rab4相互作用蛋白抗体 Broadly expressed, with highest levels in lung, testis, kidney and brain. Post-translational modifications: Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 FYVE-type zinc finger. Contains 1 RUN domain. Database links: Entrez Gene: 80230 Human Entrez Gene:Rab4相互作用蛋白抗体 216724 Mouse Entrez Gene: 360521 Rat Omim: 610327 Human SwissProt: Q96T51 Human SwissProt: Q8BIJ7 Mouse Unigene: 306769 Human Unigene: 390400 Mouse Unigene: 39348 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rab4相互作用蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 锌指蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid