磷酸二酯酶10A抗体
规格：1mg/1ml
英文名： PDE10A
别名： 5''-cyclic phosphodiesterase 10A; cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3''; cAMP and cAMP-inhibited cGMP 3'5'-cyclic phosphodiesterase 10A; FLJ1
分子量： 90kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDE10A
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
磷酸二酯酶10A抗体产品介绍：background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011] Function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. Subcellular Location: Cytoplasm. Located mostly to soluble cellular fractions. Tissue Specificity:磷酸二酯酶10A抗体 Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. Contains 2 GAF domains.磷酸二酯酶10A抗体 Database links: Entrez Gene: 10846 Human Entrez Gene: 23984 Mouse Entrez Gene: 63885 Rat Omim: 610652 Human SwissProt: Q9Y233 Human SwissProt: Q8CA95 Mouse SwissProt: Q9QYJ6 Rat Unigene: 348762 Human Unigene: 87161 Mouse Unigene: 44869 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二酯酶10A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid