28S核糖体蛋白S33抗体
规格:1mg/1ml
英文名: RT33/MRPS33
别名: 28S ribosomal protein S33; 28S ribosomal protein S33, mitochondrial; AI841153; CGI 139; FLJ21123; Ganglioside induced differentiation associated protein 3; Gdap3; MGC106490; mitochondrial; MRP S33; MR
分子量: 13kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RT33/MRP
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
28S核糖体蛋白S33抗体产品介绍:background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. 28S核糖体蛋白S33抗体elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008] Function: Displays low GTPase activity and exist predominantly in the GTP-bound form. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side Tissue Specificity: Highly 28S核糖体蛋白S33抗体expressed in heart and brain. Similarity: Belongs to the small GTPase superfamily. Di-Ras family. Database links: Entrez Gene: 51650 Human Entrez Gene: 14548 Mouse Omim: 611993 Human SwissProt: Q9Y291 Human SwissProt: Q9D2R8 Mouse Unigene: 416207 Human Unigene: 377071 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
28S核糖体蛋白S33抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid