磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
规格:1mg/1ml
英文名: phospho-RSK1 p90 (Ser221)
别名: RSK1 p90 (phospho S221); p-RSK1 p90 (phospho S221); 90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1; dJ590P13.1; EC 2.7.11.1; HU 1; HU1; KS6A1_HUMAN;
分子量: 90kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核 细胞浆
磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体产品介绍:background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体 factor CREB. Post-translational modifications: Autophosphorylated on Ser-380, as part of the activation process. Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 2 protein kinase domains. Gene ID: 6195 Database links: Entrez Gene: 6195 Human Entrez Gene: 磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体20111 Mouse Entrez Gene: 81771 Rat Omim: 601684 Human SwissProt: Q15418 Human SwissProt: P18653 Mouse SwissProt: Q63531 Rat Unigene: 149957 Human Unigene: 301827 Mouse Unigene: 34915 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid