核糖体蛋白S7抗体
规格:1mg/1ml
英文名: RPS7
别名: 40S ribosomal protein S7; DBA8; Ribosomal protein S7; RPS 7; rps7; RS7_HUMAN; S7.
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RPS7
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位:细胞核 细胞浆
核糖体蛋白S7抗体产品介绍:background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] Function: Required for rRNA maturation. DISEASE: Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased 核糖体蛋白S7抗体risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Similarity: Belongs to the ribosomal protein S7e family. Database links: Entrez Gene: 505507 Cow Entrez Gene: 6201 Human Entrez Gene: 20115 Mouse Entrez Gene: 29258 Rat Entrez Gene: 393725 Zebrafish Omim: 603658 Human SwissProt: A6H769 Cow SwissProt: P62081 Human SwissProt: P62082 Mouse SwissProt: P62083 Rat SwissProt: 核糖体蛋白S7抗体P62084 Zebrafish Unigene: 7187 Cow Unigene: 534346 Human Unigene: 546287 Human Unigene: 646582 Human Unigene: 279839 Mouse Unigene: 371579 Mouse Unigene: 107039 Rat Unigene: 224475 Rat Unigene: 28230 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核糖体蛋白S7抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 转录调节因子 激酶和磷酸酶 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid