磷酸化S6核糖体蛋白抗体
规格：1mg/1ml
英文名： phospho-RPS6 (Ser235)
别名： RPS6 (phospho S235); p-RPS6 (phospho S235); 40S ribosomal protein S6; Air8; NP33; Phosphoprotein NP33; Pp30; Ribosomal protein S6; RP S6; rps6; RS6; RS6_HUMAN; S6.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat,
细胞定位：
磷酸化S6核糖体蛋白抗体产品介绍：background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through 磷酸化S6核糖体蛋白抗体the genome. [provided by RefSeq, Jul 2008] Function: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Post-translational modifications: Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Similarity: Belongs to the ribosomal protein S6e family. Database links: Entrez Gene: 6194 Human Entrez Gene: 20104 Mouse Entrez 磷酸化S6核糖体蛋白抗体Gene: 667739 Mouse Entrez Gene: 29304 Rat Omim: 180460 Human SwissProt: P62753 Human SwissProt: P62754 Mouse SwissProt: P62755 Rat Unigene: 408073 Human Unigene: 379007 Mouse Unigene: 425090 Mouse Unigene: 34341 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化S6核糖体蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid