甲基化样蛋白1抗体
规格:1mg/1ml
英文名: METTL1
别名: C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like 1; Methyltransferase like protein 1; Methyltransferase-like protein 1; Mettl1; TRM8; TRMB_HUMAN; TRMT8; tRNA (guanine N(7) ) methyltr
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human METTL1
交叉反应:Human, Mouse, Cow,
细胞定位:细胞核
甲基化样蛋白1抗体产品介绍:background: This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008] Function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Subcellular Location: Nucleus. Tissue Specificity:甲基化样蛋白1抗体 Ubiquitous. Post-translational modifications: Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4. Similarity: Belongs to the methyltransferase superfamily. TrmB family. Database links: Entrez Gene: 511197 Cow Entrez Gene: 4234 Human Entrez Gene: 17299 Mouse GenBank: BC000550 Human Omim: 604466 Human SwissProt: Q2YDF1 Cow SwissProt: Q9UBP6 甲基化样蛋白1抗体Human SwissProt: Q9Z120 Mouse Unigene: 42957 Human Unigene: 251593 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲基化样蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid