甲基样蛋白16抗体
规格：1mg/1ml
英文名： METT10D
别名： 2610100D03Rik; 2810013M15Rik; A830095F14Rik; AI846133; Methyltransferase 10 domain containing; Methyltransferase like 16; METT10D; MGC3329; OTTMUSP00000006473; Putative methyltransferase METT10D; RP23
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human METT10D
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, Chimpanzee,
细胞定位：细胞核
甲基样蛋白16抗体产品介绍：background: METT10D is a 562 amino acid protein that belongs to the METTL16/rlmF family and methyltransferase superfamily. A putative methyltransferase, METT10D exists as two alternatively spliced isoforms and undergoes phosphorylation in response to DNA damage, most likely by Atm or ATR. The gene encoding METT10D maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is 甲基样蛋白16抗体directly involved in DNA repair, and is linked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes. Function: Probable methyltransferase. Similarity: Belongs to the methyltransferase superfamily. METTL16/RlmF family. Database links: Entrez 甲基样蛋白16抗体Gene: 468142 Chimpanzee Entrez Gene: 100765063 Chinese Hamster Entrez Gene: 480655 Dog Entrez Gene: 100734997 Guinea pig Entrez Gene: 79066 Human Entrez Gene: 67493 Mouse Entrez Gene: 360568 Rat SwissProt: Q86W50 Human SwissProt: Q9CQG2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲基样蛋白16抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid