中胚层特异性转录同源蛋白MEST抗体
规格:1mg/1ml
英文名: MEST
别名: DKFZp686L18234; EC 3.-.-.-; Mesoderm specific transcript (mouse) homolog; Mesoderm specific transcript homolog (mouse); Mesoderm-specific transcript homolog protein; MEST; MEST_HUMAN; MGC111102; MGC87
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MEST
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:
中胚层特异性转录同源蛋白MEST抗体产品介绍:background: This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011] Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific 中胚层特异性转录同源蛋白MEST抗体manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is中胚层特异性转录同源蛋白MEST抗体 expressed from both the paternal allele and the maternal allele. Similarity: Belongs to the AB hydrolase superfamily. Gene ID: 4232 Database links: Entrez Gene: 4232 Human Entrez Gene: 404180 Cow Entrez Gene: 607717 Dog Entrez Gene: 17294 Mouse Entrez Gene: 100147710 Pig Entrez Gene: 58827 Rat Omim: 601029 Human SwissProt: Q2HJM9 Cow SwissProt: Q5EB52 Human SwissProt: Q07646 Mouse SwissProt: Q6P5P5 Rat Unigene: 270978 Human Unigene: 59431 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中胚层特异性转录同源蛋白MEST抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 转录调节因子 **细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid