Rad52抗体
规格：1mg/1ml
英文名： Rad52
别名： DNA repair protein RAD52; DNA repair protein RAD52 homolog; RAD 52; RAD52 homolog (S. cerevisiae); RAD52 homolog; Recombination protein RAD52; Rhabdomyosarcoma antigen MU RMS 40.23; DNA repair protein
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Rad52
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
Rad52抗体产品介绍：background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008] Function: Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of Rad52抗体complementary single-stranded DNA and by stimulation of the RAD51 recombinase. Subunit: The full-length protein forms heptameric rings. Interacts with ABL1. Subcellular Location: Nucleus (Potential). Post-translational modifications: Phosphorylated upon DNA Rad52抗体damage by ABL1, and probably by ATM or ATR. Similarity: Belongs to the RAD52 family. Gene ID: 5893 Database links: Entrez Gene: 5893 Human Omim: 600392 Human SwissProt: P43351 Human Unigene: 410355 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rad52抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：染色质和核信号 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid