MEMO1蛋白抗体
规格:1mg/1ml
英文名: MEMO1
别名: C21orf19-like protein; C2orf4; CGI 27; DKFZp434I0135; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-drive
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MEMO1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:细胞膜
MEMO1蛋白抗体产品介绍:Function: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. Subunit: Interacts with ERBB2 phosphorylated on 'Tyr-1248'. Similarity: Belongs to the UPF0103MEMO1蛋白抗体 family. Gene ID: 51072 Database links: Entrez Gene: 51072 Human Entrez Gene: 615803 Cow Entrez Gene: 76890 Mouse Entrez Gene: 298787 Rat Entrez Gene: 327360 Zebrafish Omim: 611786 Human SwissProt: Q2HJH7 Cow SwissProt: Q9Y316 Human SwissProt:MEMO1蛋白抗体 Q91VH6 Mouse SwissProt: Q4QQR9 Rat SwissProt: Q803S3 Zebrafish Unigene: 43892 Cow Unigene: 444969 Human Unigene: 311874 Mouse Unigene: 22312 Rat Unigene: 14259 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MEMO1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 激酶和磷酸酶 结合蛋白 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid