MED8蛋白抗体
规格：1mg/1ml
英文名： MED8
别名： Activator recruited cofactor 32 kDa component; Activator-recruited cofactor 32 kDa component; ARC32; med8; MED8_HUMAN; Mediator complex subunit 8; Mediator of RNA polymerase II transcription subunit 8
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MED8
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位：细胞核
MED8蛋白抗体产品介绍：background: This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves MED8蛋白抗体as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins. Subcellular Location: Nucleus. Similarity: Belongs to the Mediator complex subunit 8 family. Database links: Entrez Gene: 112950 Human MED8蛋白抗体Entrez Gene: 80509 Mouse Entrez Gene: 362575 Rat Entrez Gene: 404615 Zebrafish Omim: 607956 Human SwissProt: Q96G25 Human SwissProt: Q9D7W5 Mouse SwissProt: Q6NYT1 Zebrafish Unigene: 301756 Human Unigene: 259567 Mouse Unigene: 229078 Rat Unigene: 84281 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产MED8蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid