前列腺素E受体3抗体
规格：1mg/1ml
英文名： EP3/PTGER3
别名： EP 3; EP3; EP3 I; EP3 II; EP3 III; EP3 IV; Ep3 prostanoid receptor; Ep3 receptor; EP3 subtype; EP3e; HGNC:9595; MGC141828; MGC141829; MGC27302; PE2R3_HUMAN; PGE receptor EP3 subtype; PGE2 R; PGE2 rece
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EP3
交叉反应：Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位：细胞膜
前列腺素E受体3抗体产品介绍：background: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Function: Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to 前列腺素E受体3抗体both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels. 前列腺素E受体3抗体Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 5733 Database links: Entrez Gene: 5733 Human Entrez Gene: 19218 Mouse Entrez Gene: 24929 Rat Omim: 176806 Human SwissProt: P43115 Human SwissProt: P30557 Mouse SwissProt: P34980 Rat Unigene: 445000 Human Unigene: 30424 Mouse Unigene: 10361 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列腺素E受体3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid