肺癌转移相关蛋白1抗体
规格:1mg/1ml
英文名: MED19/LCMR1
别名: LCMR1; Lung cancer metastasis related protein 1; Lung cancer metastasis-related protein 1; med19; MED19_HUMAN; Mediator complex subunit 19; Mediator of RNA polymerase II transcription subunit 19; Medi
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MED19/LC
交叉反应:Human, Mouse, Rat, Chicken, Cow, Horse,
细胞定位:细胞核
肺癌转移相关蛋白1抗体产品介绍:background: MED19 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008] Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation肺癌转移相关蛋白1抗体 complex with RNA polymerase II and the general transcription factors. Subcellular Location: Nucleus.肺癌转移相关蛋白1抗体 Similarity: Belongs to the Mediator complex subunit 19 family. Gene ID: 219541 Database links: Entrez Gene: 219541 Human Entrez Gene: 509245 Cow Entrez Gene: 612925 Dog Entrez Gene: 100066998 Horse Entrez Gene: 381379 Mouse Entrez Gene: 100520359 Pig Entrez Gene: 311165 Rat Omim: 612385 Human SwissProt: A0JLT2 Human SwissProt: Q8C1S0 Mouse Unigene: 43619 Human Unigene: 219643 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肺癌转移相关蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid