前纤维蛋白2抗体
规格：1mg/1ml
英文名： Profilin 2
别名： D3S1319E; PFL; PFN 2; PFN2; Profilin II; Profilin-2; Profilin 2; Profilin2; ProfilinII; Profilin II; Profilin-II; PFN2; PROF2_HUMAN
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Profilin
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位：
前纤维蛋白2抗体产品介绍：background: Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung. Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Subunit: Occurs in many kinds of cells as a 前纤维蛋白2抗体complex with monomeric actin in a 1:1 ratio. Subcellular Location: Cytoplasm, cytoskeleton. Tissue Specificity: Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. Similarity: Belongs to the profilin family. Gene ID: 5217 Database links: Entrez Gene: 5217 Human Entrez Gene: 18645 Mouse Entrez Gene: 81531 Rat Omim: 176590 Human SwissProt: P35080 Human SwissProt: 前纤维蛋白2抗体Q9JJV2 Mouse SwissProt: Q9EPC6 Rat Unigene: 91747 Human Unigene: 271744 Mouse Unigene: 203100 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 前纤维蛋白(profilin)是一种低分子量的肌动蛋白结合蛋白, 前纤维蛋白除了能与肌动蛋白结合之外,在分子间相互作用前纤维蛋白2抗体的复杂网络中还起到一个控制中心的作用。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid