锌指蛋白743抗体
规格：1mg/1ml
英文名： ZNF743
别名： MBD2 Interacting Zinc Finger MIZF; DKFZp434F162; HiNF-P; HINFP; HINFP_HUMAN; Histone H4 gene specific protein HiNF P; Histone H4 transcription factor; Histone nuclear factor P; MBD2 (methyl-CpG-bindin
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF743
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位：细胞核
锌指蛋白743抗体产品介绍：background: This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011] Function: Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. Subcellular Location: Nucleus. Associated with discrete nuclear foci. Tissue Specificity: Ubiquitous. 锌指蛋白743抗体Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver. Post-translational modifications: Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation. Similarity: Contains 9 C2H2-type zinc fingers. Database links:锌指蛋白743抗体 Entrez Gene: 511965 Cow Entrez Gene: 25988 Human Entrez Gene: 102423 Mouse Entrez Gene: 300665 Rat Entrez Gene: 406733 Zebrafish Omim: 607099 Human SwissProt: Q2TBP2 Cow SwissProt: Q9BQA5 Human SwissProt: Q8K1K9 Mouse Unigene: 504091 Human Unigene: 24570 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产锌指蛋白743抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid