甲硫氨酸转运RNA合成酶抗体
规格：1mg/1ml
英文名： MARS
别名： cytoplasmic; Mars; Methionine tRNA ligase 1, cytoplasmic; Methionine tRNA ligase; Methionine tRNA synthetase; Methionine--tRNA ligase; Methionyl tRNA synthetase; Methionyl-tRNA synthetase; MetRS; MTRN
分子量： 101kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MARS
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：细胞浆
甲硫氨酸转运RNA合成酶抗体产品介绍：background: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011] Subunit: Component of the multisynthetase complex which is comprised of a bifunctional glutamyl-prolyl-tRNA synthetase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl, and aspartyl-tRNA synthetases as well as three auxiliary proteins, p18, p48 and p43.甲硫氨酸转运RNA合成酶抗体 Subcellular Location: Cytoplasm. DISEASE: Infantile liver failure syndrome 2 (ILFS2) [MIM:615486]: A life-threatening disorder of hepatic function that manifests with liver failure in the first months of life. Clinical features include failure to thrive, hypotonia, intermittent lactic acidosis, aminoaciduria, hypothyroidism, interstitial lung disease, anemia, liver canalicular cholestasis, steatosis, and iron deposition. 甲硫氨酸转运RNA合成酶抗体Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. Contains 1 GST C-terminal domain. Contains 1 WHEP-TRS domain. Gene ID: 4141 Database links: Entrez Gene: 4141 Human Entrez Gene: 216443 Mouse Entrez Gene: 299851 Rat Omim: 156560 Human SwissProt: P56192 Human SwissProt: Q68FL6 Mouse Unigene: 632707 Human Unigene: 28173 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲硫氨酸转运RNA合成酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid