MAPK/ERK激酶激酶15抗体
规格:1mg/1ml
英文名: MAP3K15
别名: Apoptosis signal-regulating kinase 3; ASK3; bA723P2.3; FLJ16518; M3K15_HUMAN; Map3k15; MAPK/ERK kinase kinase 15; MEK kinase 15; MEKK 15; Mitogen activated protein kinase kinase kinase 15; Mitogen-act
分子量: 147kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MAP3K15
交叉反应:Human, Mouse,
细胞定位:细胞浆 细胞膜
MAPK/ERK激酶激酶15抗体产品介绍:background: The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses. [provided by RefSeq, Jul 2010] Function: May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis. Tissue Specificity: Isoform 2 and isoform 3 are widelyMAPK/ERK激酶激酶15抗体expressed. Isoform 2 highest levels are observed in fetal brain, and isoform 3 highest levels in pancreas, peripheral blood leukocytes, fetal brain and spleen. Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinaseMAPK/ERK激酶激酶15抗体 kinase subfamily. Contains 1 protein kinase domain. Database links: Entrez Gene: 389840 Human Entrez Gene: 270672 Mouse Omim: 300820 Human SwissProt: Q6ZN16 Human SwissProt: A2AQW0 Mouse Unigene: 713701 Human Unigene: 386889 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MAPK/ERK激酶激酶15抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid