甘露糖苷酶α胞浆抗体
规格：1mg/1ml
英文名： MAN2C1
别名： alpha D mannoside mannohydrolase; alpha mannosidase 2C1; Alpha mannosidase 6A8B; Alpha-D-mannoside mannohydrolase; Alpha-mannosidase 2C1; MA2C1_HUMAN; Man2c1; MAN6A8; MANA; MANA1; Mannosidase alpha 6A
分子量： 114kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAN2C1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
甘露糖苷酶α胞浆抗体产品介绍：background: Misfolded glycoproteins are deglycosylated by the peptide N-glycanase during the degradation process. Free oligosaccharides released by N-glycanase are catabolized by cytosolic MAN2C1, also designated alpha-mannosidase 2C1. MAN2C1, a member of the glycosyl hydrolase 38 family, can cleave alpha 1,2-linked, alpha 1,3-linked and alpha 1,6-linked mannose residues and is stimulated by cobalt. The furanose analogs, swainsonine (SW) and 1,4-dideoxy-1,4-imino-d-mannitol (DIM), are known甘露糖苷酶α胞浆抗体 inhibitors of MAN2C1. The inhibition of MAN2C1 can enhance the adhesion of Jurkat T cells, showing a cytoskeletal rearrangement of the cells. Similarity: Belongs to the glycosyl hydrolase 38 family. Database links: Entrez Gene: 4123 Human Omim: 154580 Human 甘露糖苷酶α胞浆抗体SwissProt: Q9NTJ4 Human Unigene: 26232 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甘露糖苷酶α胞浆抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid