恶性纤维组织细胞瘤抗体
规格：1mg/1ml
英文名： MFHA1/Malignant fibrous histiocytoma
别名： Malignant fibrous histiocytoma-amplified sequence 1; Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1; MFHA1_HUMAN; Mfhas1.
分子量： 117kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MFHA1/Ma
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
恶性纤维组织细胞瘤抗体产品介绍：background: Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008] Tissue Specificity: Ubiquitously expressed. Overexpressed in malignant fibrous histiocytomas. DISEASE: A chromosomal aberration involving MFHAS1 may 恶性纤维组织细胞瘤抗体be a cause of B-cell lymphoma. Translocation t(8;14)(p23.1;q21) with a cryptic exon named '14q21 element'. The resulting fusion protein named 'chimeric MASL1' is tumorigenic in nude mice. Similarity: Contains 13 LRR (leucine-rich) repeats. Contains 1 Roc domain恶性纤维组织细胞瘤抗体. Database links: Entrez Gene: 9258 Human Entrez Gene: 52065 Mouse Entrez Gene: 306508 Rat SwissProt: Q9Y4C4 Human SwissProt: Q3V1N1 Mouse Unigene: 379414 Human Unigene: 103246 Mouse Unigene: 106316 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
恶性纤维组织细胞瘤抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞周期蛋白 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid