黑色素瘤相关抗原8抗体
规格:1mg/1ml
英文名: MAGEA8
别名: Cancer/testis antigen 1.8; CT1.8; MAGA8_HUMAN; MAGE 8 antigen; MAGE-8 antigen; MAGE8 antigen; MAGEA8; Melanoma antigen family A 8; Melanoma associated antigen 8; Melanoma-associated antigen 8; MGC2182
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MAGEA8
交叉反应:Human,
细胞定位:细胞浆
黑色素瘤相关抗原8抗体产品介绍:background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009] 黑色素瘤相关抗原8抗体Function: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testis and placenta. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 4107 黑色素瘤相关抗原8抗体Human Omim: 300341 Human SwissProt: P43361 Human Unigene: 522803 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑色素瘤相关抗原8抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid