黑色素瘤相关抗原D4抗体
规格：1mg/1ml
英文名： MAGD4
别名： Melanoma-associated antigen D4.
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAGD4
交叉反应：Human,
细胞定位：细胞膜
黑色素瘤相关抗原D4抗体产品介绍：background: This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes on chromosome Xp11. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases黑色素瘤相关抗原D4抗体. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Tissue Specificity: Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma黑色素瘤相关抗原D4抗体 cells among cancer cells. Detected in some renal cell carcinoma samples. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 81557 Human SwissProt: Q96JG8 Human Unigene: 522650 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑色素瘤相关抗原D4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid