转录因子MAFF抗体
规格：1mg/1ml
英文名： MAFF
别名： Avian musculoaponeurotic fibrosarcoma virus (v maf) AS42 oncogene, protein F; CTA 447C4.1; hMafF; MAFF; MAFF_HUMAN; OTTHUMP00000199299; Transcription factor MafF; U MAF; U-Maf; V maf avian musculoapon
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAFF
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
转录因子MAFF抗体产品介绍：background: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] Function: Interacts with the upstream promoter region of the oxytocin receptor gene. May be a trans转录因子MAFF抗体criptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response. Subcellular Location: Nucleus. Tissue Specificity: Expressed in the term myometrium and kidney. Similarity: Belongs to the bZIP family. Maf subfamily. Contains 1 转录因子MAFF抗体bZIP domain. Database links: Entrez Gene: 23764 Human Entrez Gene: 17133 Mouse Omim: 604877 Human SwissProt: Q9ULX9 Human SwissProt: O54791 Mouse Unigene: 517617 Human Unigene: 86646 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子MAFF抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid