蛋白激酶A锚定蛋白1抗体
规格：1mg/1ml
英文名： AKAP1
别名： A kinase anchor protein; A-kinase anchor protein 1; A-kinase anchor protein 149 kDa; AKAP 149; AKAP; Akap1; AKAP1_HUMAN; D-AKAP-1; DAKAP1; Dual specificity A-kinase-anchoring protein 1; mitochondrial;
分子量： 94kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AKAP1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆
蛋白激酶A锚定蛋白1抗体产品介绍：background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008] Function: Binds to type I and II regulatory 蛋白激酶A锚定蛋白1抗体subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. Subcellular Location: Mitochondrion outer membrane. Tissue Specificity: AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is 蛋白激酶A锚定蛋白1抗体expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma. Similarity: Contains 1 KH domain. Contains 1 Tudor domain. Gene ID: 8165 Database links: Entrez Gene: 8165 Human Omim: 602449 Human SwissProt: Q92667 Human Unigene: 463506 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白激酶A锚定蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid