20号染色体开放阅读框133抗体
规格:1mg/1ml
英文名: MACROD2/C20orf133
别名: C20orf133; MACD2_HUMAN; MACRO domain containing 2; MACRO domain-containing protein 2; macrod2; O-acetyl-ADP-ribose deacetylase MACROD2.
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MACROD2/
交叉反应:Human, Mouse,
细胞定位:细胞核
20号染色体开放阅读框133抗体产品介绍:background: MACROD2 (MACRO Domain Containing 2) is a Protein Coding gene. Diseases associated with MACROD2 include autism spectrum disorder and pervasive developmental disorder. GO annotations related to this gene include hydrolase activity, acting on glycosyl bonds and deacetylase activity. An important paralog of this gene is MACROD1. Function: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose20号染色体开放阅读框133抗体. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Subunit: Interacts with ADP-ribosylated PARP1. Subcellular Location: Nucleus. Similarity: Contains 1 Macro20号染色体开放阅读框133抗体 domain. Database links: Entrez Gene: 140733 Human Entrez Gene: 72899 Mouse SwissProt: A1Z1Q3 Human SwissProt: Q3UYG8 Mouse Unigene: 661576 Human Unigene: 229466 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
20号染色体开放阅读框133抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid