溶酶体磷脂酶3抗体
规格:1mg/1ml
英文名: LYPLA3
别名: 1 O acylceramide synthase; 1-O-acylceramide synthase; ACS; DKFZp564A0122; Group XV phospholipase A2; GXVPLA 2; GXVPLA2; LCAT like lysophospholipase; LCAT-like lysophospholipase; LLPL; LPLA 2; LPLA2; L
分子量: 47kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LYPLA3
交叉反应:Human, Mouse, Rat, Dog, Cow,
细胞定位:分泌型蛋白
溶酶体磷脂酶3抗体产品介绍:background: Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008] Function: Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid (By similarity). May溶酶体磷脂酶3抗体 have weak lysophospholipase activity. Subcellular Location: Lysosome. Secreted. Tissue Specificity: Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications: N-glycosylated. Similarity: Belongs to the AB hydrolase superfamily. Lipase family. Database links:溶酶体磷脂酶3抗体 Entrez Gene: 282271 Cow Entrez Gene: 403403 Dog Entrez Gene: 23659 Human Entrez Gene: 192654 Mouse Entrez Gene: 361401 Rat Omim: 609362 Human SwissProt: Q8NCC3 Human SwissProt: Q8VEB4 Mouse SwissProt: Q675A5 Rat Unigene: 632199 Human Unigene: 284770 Mouse Unigene: 93631 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶酶体磷脂酶3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid