异型组蛋白H2A.2抗体
规格：1mg/1ml
英文名： Macro H2A.2
别名： Core histone macro H2A2.2; Core histone macro-H2A.2; Core histone macroH2A2.2; H2A histone family member Y2; H2AFY2; H2AW_HUMAN; Histone macroH2A2; Macro H2A2; MacroH2A.2; MacroH2A2; mH2A2.
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Macro H2
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
异型组蛋白H2A.2抗体产品介绍：Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation. Subcellular Location: Nucleus. Chromosome. Enriched in inactive X chromosome异型组蛋白H2A.2抗体 chromatin and in senescence-associated heterochromatin. Similarity: Contains 1 histone H2A domain. Contains 1 Macro domain. Gene ID: 55506 Database links: Entrez Gene: 55506 Human Entrez Gene: 404634 Mouse Entrez Gene: 361844 Rat SwissProt: 异型组蛋白H2A.2抗体Q9P0M6 Human SwissProt: Q8CCK0 Mouse Unigene: 499953 Human Unigene: 272870 Mouse Unigene: 163432 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异型组蛋白H2A.2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid