ß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体
规格：1mg/1ml
英文名： Beta-phosphoglucomutase
别名： Beta PGM; pgmB; Beta-phosphoglucomutase; Glucose phosphomutase 1; Glucose phosphomutase; PGM.
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Lactococcus la
交叉反应：Lactococcus lactis
细胞定位：细胞浆
ß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体产品介绍：background: Beta-phosphoglucomutase is an enzyme that transfers a phosphoryl group on a glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse. Specifically, it converts Beta-D-glucose-1-phosphate to Beta-D-glucose-6-phosphate. This enzyme participates in both the breakdown and synthesis of glucose. Maltose metabolism in Lactococcus lactis involves the conversion of beta-glucose 1-phosphate to glucose 6-phosphate, a reaction which is reversibly catalysed by a maltose-inducible and glucose-repressible beta-phosphoglucomutase (beta-PGM). Alpha-PGM is expressed constitutively. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. The enzyme from Lactococcus lactis has been extensively characterised including a remarkable crystal structure which traps the pentacoordinate transition state. Function: Catalyzes theß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体 interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C1 anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose. Subcellular Location: ß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体Cytoplasmic Post-translational modifications: Autophosphorylated. Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. Gene ID: 1114041 Database links: Entrez Gene: 1114041 Lactococcus lacti Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 通道蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid