肌动蛋白交联蛋白家族7抗体
规格：1mg/1ml
英文名： MACF1/ACF7
别名： ABP620; Acf7; Aclp7; Actin cross linking family 7; MACF; Microtubule actin crosslinking factor 1; mKIAA0465; R74989; rabeculin alpha.
分子量： 832kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MACF1/AC
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
肌动蛋白交联蛋白家族7抗体产品介绍：background: Microtubule-actin crosslinking factor 1 (MACF1/ACF7) belongs to spectraplakin family of proteins which also includes mammalian Bpag1/dystonin, Drosophila Short Stop (Shot) and Caenorhabditis elegans Vab-10. These are large actin-microtubule linker molecules that are essential for various biological processes such as neuronal degeneration, wound healing, gastrulation. MACF1, located on mouse chromosome 4D2.2, was found to play an important role during neurogenesis- it was shown that 肌动蛋白交联蛋白家族7抗体MACF1 regulates the organization of neuronal microtubules which is essential for axon extension. Furthermore, MACF1 is required in controlling focal adhesion assembly and dynamics. MACF1 behaves as an actin-regulated ATPase and it has the 肌动蛋白交联蛋白家族7抗体ability to target microtubules that track along F-actin to focal adhesions. MACF1 was also implicated in regulating filopodia formation. Subcellular Location: Cytoplasmic, microtubule. Plasma membrane. Golgi apparatus. Database links: Entrez Gene: 11426 Mouse Entrez Gene: 362587 Rat SwissProt: Q9QXZ0 Mouse SwissProt: D3ZHV2 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌动蛋白交联蛋白家族7抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid