基质金属蛋白酶11抗体
规格：1mg/1ml
英文名： MMP11
别名： matrix metalloproteinase 11; Stromelysin-3; SL-3; Matrix metalloproteinase-11; MMP11; MMP 11; MMP-11; SL 3; SL3; ST 3; ST3; STMY 3; STMY3; Stromelysin 3; Stromelysin 3 precursor; Stromelysin III; Stro
分子量： 43/51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MMP11
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞外基质 分泌型蛋白
基质金属蛋白酶11抗体产品介绍：background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. 基质金属蛋白酶11抗体[provided by RefSeq, Jul 2008]. Function: May play an important role in the progression of epithelial malignancies. Subunit: Secreted, extracellular space, extracellular matrix (Probable). Subcellular Location: Secreted, extracellular space, extracellular matrix (Probable). Tissue Specificity: Specifically expressed in stromal cells of breast carcinomas. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. Gene ID: 4320 Database links: Entrez Gene: 4320基质金属蛋白酶11抗体 Human Entrez Gene: 17385 Mouse Entrez Gene: 25481 Rat Omim: 185261 Human SwissProt: P24347 Human SwissProt: Q02853 Mouse SwissProt: Q499S5 Rat Unigene: 143751 Human Unigene: 4561 Mouse Unigene: 11123 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
基质金属蛋白酶11抗体产品应用：WB=1:100-500 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid