色氨酸2,3双加氧酶抗体
规格:1mg/1ml
英文名: TDO2/tryptophan 2,3-dioxygenase
别名: tryptophan 2,3-dioxygenase; 3-dioxygenase; T23O_HUMAN; TDO 2; TDO; tdo2; TO; TPH2; TRPO; Tryptamin 2 3 dioxygenase; Tryptamin 2; Tryptophan 2 3 dioxygenase; Tryptophan 2; Tryptophan oxygenase; Tryptop
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TDO2/try
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞浆 细胞膜
色氨酸2,3双加氧酶抗体产品介绍:background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012] Function: Incorporates oxygen into the indole moiety of tryptophan.色氨酸2,3双加氧酶抗体 Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin Subunit: Homotetramer (By similarity). Similarity: Belongs to the tryptophan 2,3-dioxygenase family. Gene ID: 6999 Database links:色氨酸2,3双加氧酶抗体 Entrez Gene: 6999 Human Omim: 191070 Human SwissProt: P48775 Human Unigene: 183671 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
色氨酸2,3双加氧酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid