ZC3H8蛋白抗体
规格:1mg/1ml
英文名: ZC3H8
别名: Fliz1; Zc3h8; ZC3H8_HUMAN; Zinc finger CCCH domain containing protein 8; Zinc finger CCCH domain-containing protein 8.
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZC3H8
交叉反应:Human, Gorilla, Orangutan
细胞定位:细胞核
ZC3H8蛋白抗体产品介绍:Function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) ZC3H8蛋白抗体of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 3 C3H1-type zinc fingers. Database links: Entrez Gene: 84524 Human SwissProt: Q8N5P1 Human Unigene: ZC3H8蛋白抗体418416 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZC3H8蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 结合蛋白 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid