锌指蛋白711抗体
规格:1mg/1ml
英文名: ZNF711/ZNF5
别名: CMPX1; dJ75N13.1; MRX97; Zfp711; Zinc finger protein 6 (CMPX1); Zinc finger protein 6; Zinc finger protein 711; ZN711; ZN711_HUMAN; ZNF4; ZNF5; ZNF6; ZNF711.
分子量: 87kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF711/Z
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位:细胞核
锌指蛋白711抗体产品介绍:background: This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with mental retardation. [provided by RefSeq, Jul 2008] Function: Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C. Subcellular Location: Nucleus. Tissue Specificity: Expressed in neural tissues. Post-translational modifications锌指蛋白711抗体 Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Defects in ZNF711 are the cause of mental retardation X-linked ZNF711-related (MRXZ) [MIM:300803]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Similarity: Belongs to the krueppel锌指蛋白711抗体 C2H2-type zinc-finger protein family. Contains 12 C2H2-type zinc fingers. Database links: Entrez Gene: 526026 Cow Entrez Gene: 7552 Human Entrez Gene: 245595 Mouse Entrez Gene: 302327 Rat Omim: 314990 Human SwissProt: Q9Y462 Human SwissProt: A2ANX9 Mouse Unigene: 326801 Human Unigene: 259846 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白711抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:发育生物学 神经生物学 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid