锌指蛋白136抗体
规格:1mg/1ml
英文名: ZNF136
别名: pHZ 20; Zinc finger protein 136; Zinc finger protein 136 clone pHZ 20; ZN136_HUMAN; ZNF136.
分子量: 63kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF136
交叉反应:Human,
细胞定位:细胞核
锌指蛋白136抗体产品介绍:background: ZNF136 is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It is a ubiquitously expressed protein, localizes to the nucleus and contains 14 C2H2-type zinc fingers and 1 KRAB A-domain. Alone, ZNF136 functions as a weak repressor; however, when fused with a heterologous KRAB B-domain containing protein, such as ZNF10, ZNF136 functions as a potent repressor. Function: May be involved in transcriptional regulation as a weak repressor when alone, or锌指蛋白136抗体 a potent one when fused with a heterologous protein containing a KRAB B-domain. Subcellular Location: Nucleus. Tissue Specificity: Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 14 C2H2-type zinc fingers. Contains 1 KRAB domain. Gene ID: 7695 Database links: Entrez Gene: 锌指蛋白136抗体7695 Human Omim: 604078 Human SwissProt: P52737 Human Unigene: 479874 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白136抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid